Fig. 3. Hydropathy plot of (A) crayfish cardiac muscle SERCA (present study; accession no. AAB82291) in comparison with (B) crayfish axial muscle (Zhang et al., 2000; accession no. AAB8229), (C) Artemia SERCA 5.2 kb isoform (Escalante and Sastre, 1993; accession no. CAA51262), (D) Artemia SERCA 4.5 kb isoform (Palmero and Sastre, 1989; accession no. P35316), (E) rat SERCA2b (Lytton et al., 1989; accession no. P11057) and (F) rat SERCA2a (Brandl et al., 1986; accession no. P11508). Hydrophobicity values were determined by the method of Kyte and Doolittle (1982) using a window of 12 residues (MacDNASIS, Rainbow Technologies). Putative transmembrane domains are numbered based on the model of Brandl et al. (1986). The arrows indicate the extra potential transmembrane domain.