JEB -- Stevens et al. 205 (16): 2545 Figure IG8

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Fig. 8. Schematic representation of amino acid ligand-gating of cationic channel conductance in CAATCH1 (Tyr¹⁴⁷) and the Y147F (Phe¹⁴⁷) mutant. (A) Endogenous WT currents in the absence of ligands. (B) No Y147F current in the absence of ligands. (C) Increased WT currents gated by extracellular L-proline. (D) No Y147F current gated by extracellular L-proline. (E) WT Na⁺ inward current blocked by extracellular L-methionine. (F) Y147F currents enhanced by extracellular L-methionine.