Fig. 8. A model for the MYH13 gene chromosomal domain. Conserved sites identified by phylogenetic footprinting (see Fig. 7) and two bounding CpG island domains revealed by GeneQuest are shown on a map of the human chromosomal region from the end of the upstream perinatal gene to a region downstream of the MYH13 gene. Here, the sites are tentatively assigned functions as the proximal promoter, upstream regulatory elements (UREs) and a locus control region (LCR) by analogy with the model for gene organization presented by Blackwood and Kadonaga (1998). This region is drawn to scale.