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Fig. 2. Effects of 1 mmol l-1 cyclic AMP (cAMP) and 1 mmol l-1 cyclic GMP (cGMP) on fluid secretion by isolated pharate adult M. sexta Malpighian tubules. Cyclic nucleotides were added at the time indicated by the vertical line. Values are means ± 1 S.E.M. (N=5). Control trace represents data from a single trial.