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Fig. 7. Effect of 50 µmol l-1 prostaglandin E3 (PGE3), 5 µmol l-1 8-hydroxyeicosapentaenoic acid (8-HEPE) and 5 µmol l-1 12-HEPE on Ciona intestinalis heart rate expressed as a percentage of basal rate. Values are means + S.E.M., N=5-15. *Significantly different (P=0.007) compared with ethanol (vehicle) control.