Fig. 2. Histological sections of the lesion in PEG-treated and untreated spinal cords. Typical horizontal/longitudinal histological sections acquired to computer for three-dimensional reconstruction. All views shown were obtained from histological sections at the epicenter or most extensively damaged region of the lesion. A and C are typical of untreated (control) spinal cord lesions, while B and D are representative of those treated with PEG. Note the extensive cystic cavitation in control cords and the relative absence of cavitation in the PEG-treated spinal cords. In A and C, the rostral/caudal extents of the cysts are beyond the boundaries of the image. N, intact spinal cord parenchyma; L, lesion; Cy, cysts. The rostral end is to the left in all images. Scale bar (for A–D), 1 mm.