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Fig. 1. Circadian pattern of wheel-running on day 6 of a 6-day exposure to wheels in selection (filled circles) and control (open circles) lines of house mice (females) included in a videotape microanalysis of wheel-running. Values are means ± S.E.M. The graph shows the number of revolutions for each 20-min period as collected by an automated system in 1-min bins.