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Fig. 4. Rates of lactate uptake in (A) a 5 mmol l–1 intracellular:15 mmol l–1 extracellular lactate concentration gradient and (B) a 5 mmol l–1 intracellular:5 mmol l–1 extracellular concentration gradient in the presence of the monocarboxylate transporter inhibitors N-ethymaleimide (ETH) and {alpha}-cyano-4-hydroxycinnamate (CIN). Values are means ± S.E.M. for red iliofibularis (rIF) (hatched columns) and white iliofibularis (wIF) (open columns); N=4–8 in A and N=3–6 in B for each fiber type in each incubation condition. Comparisons were made only within [lactate] conditions and within fiber types. Columns with different superscripts were significantly different (P<=0.05) for statistical comparisons made between inhibitor conditions, within a muscle type. CON, control.