Fig. 3. Simulation experiments with the neuromuscular sphincter model. (A–D) The results of the partial activation experiment at various points in time (0, 350, 700 and 1050 ms, respectively); (E) the state of the uniformly activated model at 1050 ms as a control. The normalised network activity is shown in the top row. The normalised active state, the fibre strain, the pressure and the fibre stress in the sphincter are depicted in the subsequent rows. The colours in the graphs represent values indicated by the accompanying colour scales. In the pressure graph, the circular lines represent the muscle fibres, while the radial lines represent passive connective tissue fibres. In the pressure panel, the lumen is coloured, indicating the pressure in the lumen of the sphincter; the lumen has no value for strain, stress or active state.