Fig. 7. Alignments of conserved domains in Na⁺/H⁺ exchangers (NHEs). Alignment of Drosophila melanogaster NHEs and other representative NHE family members, produced using ClustalW and SeqVu software. (A) An alignment of the NHEs in the amiloride-binding region and (B) the alignment of NHEs in the highly conserved region. Blue denotes hydrophilic, and red hydrophobic, residues. Nomenclature is as for Fig. 8.