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Fig. 1. Sensitivity of secretion by the Drosophila melanogaster Malpighian tubule to inhibition by amiloride and its derivatives. Dose/response curves for amiloride, 5-N,N-dimethyl amiloride (DMA), benzamil, 5-N-ethyl-N-isopropyl amiloride (EIPA) and 2',4'-dichlorobenzamil (DCB). The upper limits of each graph are determined by the solubility of the compounds. Values are means ± S.E.M. (N=10).