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Fig. 4. Change in energy expenditure [100(hypoxic expenditure minus normoxic expenditure)/normoxic expenditure] as a function of the change in energy intake [100(hypoxic intake minus normoxic intake)/normoxic intake] from normoxia to progressive hypoxia in a hypobaric chamber (N=6; first 15-day interval, filled symbols; second 15-day interval, open symbols; r2=0.73, P<0.001).