Fig. 4. The effect of inhibiting apoptosis on follicle resorption in malaria-infected Anopheles stephensi. Immediately after feeding on a mouse containing Plasmodium yoelii nigeriensis gametocytes, mosquitoes were injected with saline (N=11), 1% DMSO in saline (N=25) or 0.5 mmoll^-1 z-VAD.fmk/1%DMSO (N=20) or left uninjected (N=20). The mean number of resorbing follicles per ovary pair is shown. Values are means ± S.E.M. A Kruskal—Wallis test demonstrated overall significance (P<0.001) followed by Mann—Whitney U-tests where all comparisons against z-VAD.fmk were significant (P<0.001). There was no significant difference between non-injected, saline-injected and DMSO-injected females.