(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)


Fig. 2. Summary of the neuroactive mediators present in the neuropile of the stomatogastric ganglion (STG) and neurohaemal organs identified either biochemically and/or by immunocytochemistry. (A) Neuroactive mediators in the STG of the crab Cancer borealis, the lobsters Homarus americanus and Homarus gammarus, the spiny lobster Panulirus interruptus and the crayfish Cherax destructor. Large circles in the drawing represent the STG somata. Mediators shown to be present are marked by a plus sign, those not present by a minus sign. The classical transmitters of the STG neurones are acetylcholine and glutamate. Only in a few cell bodies were other mediators found in both adults (a) and during development (d; see also Table 1). The source of the serotonin is the gastropyloric receptor cells (*). ACh, acetylcholine (Marder, 1987); Glu, glutamate (Marder, 1987); GABA, {gamma}-aminobutyric acid (Nusbaum et al., 1989; Cournil et al., 1990; Swensen et al., 2000); DA, dopamine (Barker et al., 1979; Kushner and Barker, 1983; Marder, 1987; Cournil et al., 1994; Cournil et al., 1995); HA, histamine (Claiborne and Selverston, 1984a; Mulloney and Hall, 1991); 5-HT, serotonin (Beltz et al., 1984; Katz et al., 1989; Kilman et al., 1999; P. Skiebe, unpublished data); Oct, octopamine (Barker et al., 1979); NO, nitric oxide (Scholz et al., 1998); AST, allatostatin (Skiebe and Schneider, 1994; Kilman et al., 1999; Skiebe, 1999); ATR, allatotropin (A. E. Christie, unpublished data); ß-PDH, ß-pigment dispersing hormone (Mortin and Marder, 1991); Buc, buccalin (Christie et al., 1994); CabTRP, Cancer borealis tachykinin-related peptide (Goldberg et al., 1988; Blitz et al., 1995; Christie et al., 1997b; Fénelon et al., 1999); CCAP, crustacean cardioactive peptide (Christie et al., 1995b; Kilman, 1998; Skiebe et al., 1999); CCK, cholecystokinin (Turrigiano and Selverston, 1991; Christie et al., 1995a; Meyrand et al., 2000; subscripts indicate different antibodies against CCK); Cor, corazonin (Christie and Nusbaum, 1995); FLRF, FLRFamide-related peptides (only FLRFamides have been isolated from crustaceans) (Marder et al., 1987; Weimann et al., 1993; Fénelon et al., 1998; Kilman et al., 1999); Myo, myomodulin (Christie et al., 1994); Proc, proctolin (Marder et al., 1986; Fénelon et al., 1998; Fénelon et al., 1999; Kilman et al., 1999; Skiebe et al., 1999); RPCH, red pigment-concentrating hormone (Nusbaum and Marder, 1988; Dickinson and Marder, 1989; Fénelon et al., 1999). (B) Summary of the neuroactive mediators present in the STG (excluding the classical transmitters ACh and Glu of STG neurones), in the pericardial organs (PO) and in the X-organ/sinus gland complex (SG) of the crab Cancer borealis and on the post-oesophageal commissure (poc), the STG and the PO of the crayfish Cherax destructor (Cancer borealis) (Christie et al., 1995b) (Cherax destructor) (Skiebe, 1999; Skiebe et al., 1999) (P. Skiebe, unpublished data). Fig.2A, left, is modified from Marder et al., 1994; Fig.2B, left, is modified from Christie et al., 1995b. stn, stomatogastric nerve; dvn, dorsal ventricular nerve.